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Óscar Fuster Lluch

Servicio de Análisis Clínicos. Hospital Universitari i Politècnic La Fe. Valencia

Wednesday, 30 September 2020

CELL CANNIBALISM AND MITOSIS IN MALIGNANT PLEURAL FLUID

Written by Óscar Fuster Lluch | Mónica Piqueras Rodríguez | Rocío Andreu Escrivá

CANIBALISMO CELULAR Y MITOSIS EN LÍQUIDO PLEURAL MALIGNO
Figure 2. Cannibalism and cell in mitosis. In the figure, a cell mitosis can be seen in the upper central part, accompanied in the lower right part of the figure by multiple cells in which cannibalism can be observed. (Pleural fluid smear. Quick panoptic stain. 600x).

An image of a pleural fluid smear stained with quick panoptic is presented. The figure shows abundant atypical cells and cell cannibalism phenomenon that suggest a neoplastic origin (figure_1). The situation described was observed in many fields of pleural fluid smear, along with abundant atypical nest cells with mitosis phenomena (figure 2).

Monday, 30 September 2019

PAPPENHEIMER BODIES IN PERIPHERAL BLOOD MORPHOLOGY

Written by Luiza Tofan | Carlos Navarro Morante | Óscar Fuster Lluch , Posted in Volumen11

CUERPOS DE PAPPENHEIMER EN MORFOLOGÍA DE SANGRE PERIFÉRICA
Figure 1. Pappenheimer bodies in erythroblast and in hemocyte (Blood smear. May-Grünwald Giemsa stain).
We present an image of a peripheral blood smear, stained with May-Grünwald Giemsa (Figure 1). This picture shows erythrocytes with multiple inclusions of bluish, small and irregular granules that occupy a portion of the red blood cell. The inclusions described are also observed in erythroblasts, adopting a perinuclear disposition. These granules, suggestive of Pappenheimer bodies, are morphologically different from other visible inclusions with the same type of staining (Howell-Jolly and basophilic stippling). This corresponds to intracellular iron deposits which were evidenced later by Perls staining (Figure 2).